Leslie Charleson, who was born on February 22, 1945 in Kansas City, Missouri, is a popular figure in daytime television as she has appeared in a number of television shows. She launched her career appearing in the short lived soap opera A Flame in the Wind in 1964. She moved to As the World Turns
to play Alice Whipple but disliked the length of the contract, thus not pushing through signing it. In 1967 she was cast for Love is a Many Splendored Thing where she played Iris Donnelly Garrison. Ten years later, Charleson was cast for the role of Monica Webber Quartermaine in replacement of Patsy Rahn in the soap opera General Hospital. It was a turbulent time for the soap when she got cast as the hair and wardrobe people at ABC were on strike, so she had to bring her own clothes and do her own make up. Moreover, the producers of General Hospital never informed the cast and crew about Rahn's dismissal, so she had to be the one to let them know. After all the struggles and challenges, however, Charleson's appearance on the soap actually helped its ratings shoot up to the number one spot.
Dr. Monica Quartermaine is played by Leslie Charleson on the soap opera General Hospital. Monica hails from the wealthy family of her husband, Alan Quartermaine. Among the many issues that she has faced throughout her marriage are breast cancer, the loss of her two children and her adopted son's amnesia and decision to become part of the mafia. She has been married twice, first to Jeff Webber and later to Alan Quartermaine, with whom she had three children with.