I think eventually she will. This isn't like when Kurt came out. Nearly everyone already knew he was gay, and he wasn't every popular, so he didn't have much to lose. Santana, however, is considered to be the hottest girl in school, and until Brittany let the news slip on her show, there were only, what, three people who knew the truth? I think this plot will drag on into the third season, but it'll eventually come to a close.