Patricia Wettig was born on December 4, 1951 in Cincinnati, Ohio. She was popularly known for her role as Nancy Weston on the show Thirtysomething. In addition, she appeared in several television programs like L.A. Law, Frasier and Hill Street Blues. She also had recurring roles on Alias and Prison Break. Ultimately, she is part of the television series Brothers & Sisters as Holly Harper. Holly Harper is the mysterious woman who is perceived to bring the Walkers and their company down.