Christina Applegate is Samantha Newly, a woman whose hit-and-run car accident leaves her in an eight-day coma. When she wakes with retrograde amnesia, she must start over and piece together who she was, discovering that she wasn't such a great person after all, but was in fact self-involved, narcissistic, and devoid of real relationships. Here her journey begins as she makes her way to being good while fighting the temptation to be bad. Samantha Who? airs on ABC.