Katherine Heigl's career kicked off when she was tapped as a child model, which led to appearances in several catalogs and television commercials. She made her acting debut in the 1992 film That Night, and took her first major role 1994's My Father The Hero.
Heigl made her big break in 1999, when she was cast as Isabel Evans in the television series Roswell. The role, which she played until 2002, led to many other film and TV projects, as well as magazine spreads. But her biggest role to date came in 2005, when she joined the cast of ABC's Grey's Anatomy as struggling medical intern Izzie Stevens.
Heigl's work on Grey's Anatomy led to an Emmy win, for Best Supporting Actress in a Drama Series, in 2007. It also led to more high-profile film projects, starting with the 2006 Judd Apatow flick Knocked Up, and later including romantic comedies The Ugly Truth and 27 Dresses. Heigl left Grey's Anatomy in 2010, purportedly to focus on her family.
Heigl married singer Josh Kelley in 2007, after a year-long engagement. They have an adopted daughter.
- One of her brothers, Jason, died from head injuries suffered in a car accident when she was very young.
- She auditioned for all three female lead roles on Roswell before being cast as Isabel.
- She is half Irish and half German.
- She played the cello in High School.
- She shared the same birthday as her former Roswell co-star Colin Hanks.
- She has played a character with the name of "Isabel" or "Isobel" three times: in Grey's Anatomy, Roswell and the TV movie Wuthering Heights.
- Character and Morality in Entertainment Award, 2003 (for Love Comes Softly)
- Character and Morality in Entertainment Award, 2005 (for Love's Enduring Promise)
- Emmy Award, Outstanding Supporting Actress in a Drama Series, 2007 (for Grey's Anatomy)
- Screen Actors Guild Award, Outstanding Performance by an Ensemble in a Drama Series, 2007 (for Grey's Anatomy)
- People's Choice Award, Favorite Female TV Star, 2008
- People's Choice Award, Favorite TV Drama Actress, 2010
- ShoWest Award, Female Star of the Year, 2010
- That Night (1992)
- King of the Hill (1993)
- My Father the Hero (1994)
- Under Siege 2: Dark Territory (1995)
- Prince Valiant (2007)
- Stand-ins (1997)
- Bug Buster (1998)
- Brice of Chucky (1998)
- 100 Girls (2000)
- Valentine (2001)
- Descendant (2003)
- Side Effects (2005)
- The Ringer (2005)
- Zyzzyx Rd (2006)
- Caffeine (2006)
- Knocked Up (2007)
- 27 Dresses (2008)
- The Ugly Truth (2009)
- Killers (2010)
- Life As We Know It (2010)
- Roswell (regular, 1999-2002)
- Grey's Anatomy (regular, 2005-2010)
On her role in My Father the Hero: "There are still men who come up to me today and say, 'You were really hot in that film!' I was 14, for God's sake!"
On her role in Roswell: "One of the most interesting things about that show for me was that because Isabel was an alien, I got to do many things, so that was creatively satisfying. I think anyone's fear of getting involved in a show that could run for several years is that you'll be playing only one character for that long; that can get stale for an actor, so on Roswell I really lucked out."
"I'm grateful people think I'm beautiful or think I'm sexy, and I suppose it's better than the alternative, but I do try to fight it a bit so it's not all people see me as. And I'd love to one day be in a position where I could choose a role to showcase my creativity versus just my bra size."
"I love changing my look. I would love, love, love to cut all my hair off into a really short, punky haircut."
During her Emmy acceptance speech: "My own mother told me I didn't have a shot in hell of winning tonight."