In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level and a patient makes Owen reassess his place at Seattle Grace.

This is it, kids. The finale of Grey‘s Anatomy season 5.  This should be good. Box(ex) of Kleenex ready?  Let‘s go.The first of the two-part finale opens, as usual, with aerial shots of Seattle.  Meredith‘s (Ellen Pompeo) doing the voiceover, and she‘s saying something about things not ending the way you planned them, in obvious reference to what happened with her non-wedding day. We see Mer and Derek (Patrick Shepherd) cuddling on the floor on the morning after. She remembers the one-night stand (Derek) that led to this moment. And to top it all off, Derek figured out a way to get Izzie‘s tumor. Everything‘s hanky-dory.
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