Rosanna Arquette was born on August 10, 1959 in New York. Aside from being an actress, she is also a film director and a producer. Initially, she portrayed roles which depicted troubled teens. Eventually, she landed more mature and promising roles. She was included in projects such as The Executioner's Song, Baby It's You, Desperately Seeking Susan, After Hours and Pulp Fiction. Later, she appeared nude in Playboy magazine's September issue. Now, she is part of the series What About Brian where she plays Nicole Varzi. Nicole Varzi is Brian's older sister who is married to Angelo. She is a record executive struggling to start a family. Balancing her career and personal life has put some strain in their marriage.